Table 1 The Demographic details of study samples.
Patient characteristic | nuc ish n = 182 (%) | qRT-PCR n = 154 (%) | IHC n = 209 (%) |
|---|---|---|---|
Total study samples | |||
OSCC | 182 | 135 | 132 |
Leukoplakia (OPL) | NA | NA | 57 |
Healthy Normal | NA | 19 | 20 |
Age at diagnosis | |||
Median (IQR) | 50 (42–58) | 50 (42–59) | 47 (39–57) |
Gender | |||
Male | 138 (75.8%) | 101 (75%) | 169 (81%) |
Female | 44 (24.2%) | 34 (25%) | 40 (19%) |
Site of OSCC | |||
Gnigivobuccal complex | 150 (82.4%) | 135 (100%) | 162 (85.7%) |
Tongue | 32 (17.6%) | 0 (0%) | 27 (14.3%) |
Pathological stage | |||
Stage 1 and 2 (Early stage OSCC) | 33 (18.1%) | 56 (41.5%) | 25 (18.9%) |
Stage 3 and 4 (Advanced stage OSCC) | 149 (81.9%) | 79 (58.5%) | 107 (81.1%) |
Pathological cervical lymph node involvement (N) | |||
Node negative (N0) | 94 (51.6%) | 79 (58.5%) | 79 (59.8%) |
Node positive (N+) | 88 (48.4%) | 56 (41.5%) | 53 (40.2%) |
Pathological grade | |||
Well | 11 (6.1%) | 12 (8.9%) | 9 (6.8%) |
Moderate | 126 (69.2%) | 87 (64.4%) | 82 (62.1%) |
Poor | 45 (24.7%) | 36 (26.7%) | 41 (31.1%) |
Treatment | |||
Surgery | 52 (28.6%) | 60 (44.4%) | 5 (3.8%) |
Surgery + RT | 78 (42.9%) | 62 (46.0%) | 79 (59.8%) |
Surgery + CT | 4 (2.2%) | 1 (0.7%) | NA |
Surgery + RT + CT | 48 (26.3%) | 12 (8.9%) | 48 (36.4%) |
Radiation compliant cases | |||
50–60 Gy | 93 (51.1%) | 63 (47%) | 85 (64.4%) |
<50 Gy | 89 (48.9%) | 72 (53%) | 2 (1.5%) |
No information | NA | NA | 45 (34.1%) |
Habit profile | |||
No Habit | 3 (1.6%) | 3 (2.2%) | 8 (4.2%) |
Exclusive tobacco users | 63 (34.6%) | 79 (58.5%) | 66 (34.9%) |
Exclusive smoker | 3 (1.7%) | 2 (1.5%) | 16 (8.5%) |
Mixed habit** | 32 (17.6%) | 28 (20.7%) | 62 (32.8%) |
No information | 81 (44.5%) | 23 (17%) | 37 (19.6%) |
