Figure 3
From: Resident Microbiome Disruption with Antibiotics Enhances Virulence of a Colonizing Pathogen
Effects of prior β-lactam antibiotic perturbation on Mycoplasma gallisepticum sialidase activity, and the relationship between sialidase activity and tissue inflammation at the time of MG isolation. (a) Mycoplasma gallisepticum recovered from house finches treated with topical antibiotics (Short + L ong treatments) to disrupt their resident ocular microbiomes had enhanced sialidase enzyme activity (mean ± standard error) on day 8 post-inoculation. (b) Sialidase activity of recovered isolates positively correlated with host tissue inflammation on the day of isolation. Because sialidase and cytadherence were strongly correlated (R = 0.98) and thus cannot be considered as independent, results are shown for sialidase enzyme activity only.
