Figure 6
From: The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence
The influence of recombinant LKA1gp49 depolymerase on PAO1 virulence tested in Galleria mellonella infection model. (A) Larvae treatment with 50 µg/ml LKA1gp49 depolymerase; (B) Larvae treatment with 5 µg/ml LKA1gp49 depolymerase; (C) Larvae infected with PAO1 cells pretreated with 5 µg/ml LKA1gp49 depolymerase for 1 hour. The control consisted of infected larvae without therapy. Statistical analysis was calculated for pair wise comparisons between infected larvae and phage treated infected larvae using Mantel-Cox test (denoted P-values < 0.05).
