Table 3 Genotype and allele frequency of GAL3ST4 polymorphism in leprosy cases and healthy controls stratified by gender and adjusted by ethnicity and age.
From: Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy
Gender | Group | Genotype | HWE test p | ||||
|---|---|---|---|---|---|---|---|
AA(%) | GG(%) | AG(%) | A(%) | G(%) | |||
Male | Leprosy (N = 99) | 49(49.5) | 9(9.1) | 41(41.4) | 139(70.2) | 59(29.8) | 0.92 |
Control (N = 112) | 48(42.9) | 15(13.4) | 49(43.7) | 145(64.7) | 79(35.3) | 0.66 | |
OR (95%CI) | 1.01 (0.51–2.0) | 1.46 (0.51–4.2) | 0.98 (0.5–1.9) | 1.1 (0.69–1.8) | 0.89 (0.6–1.4) | ||
P | 0.5 | 0.97 | 0.48 | 0.64 | |||
Female | Group | AA(%) | GG(%) | AG(%) | A(%) | G(%) | |
Leprosy (N = 52) | 13(25) | 13(25) | 26(50) | 52(50) | 52(50) | 1 | |
Control (N = 114) | 54(47.4) | 15(13.2) | 45(39.4) | 153(67.1) | 75(32.9) | 0.26 | |
OR (95%CI) | 0.3 (0.12–0.74) | 3.75 (1.2–12.1) | 3.16 (1.2–8.2) | 0.58 (0.28–0.85) | 1.68 (1.2–3.1) | ||
P | 0.009 | 0.027 | 0.018 | 0.004 | |||
Total | Group | AA(%) | GG(%) | AG(%) | A(%) | G(%) | |
Leprosy (N = 151) | 62(41.1) | 22(14.6) | 67(44.3) | 191(63.2) | 111(36.8) | 0.58 | |
Control (N = 226) | 102(45.1) | 30(13.3) | 94(41.6) | 298(65.9) | 154(34.1) | 0.26 | |
OR (95%CI) | 0.95 (0.46–1.9) | 0.72 (0.43–1.2) | 0.68 (0.33–1.4) | 0.78 (0.51–1.1) | 1.26 (0.89–1.8) | ||
P | 0.88 | 0.219 | 0.31 | 0.194 | |||
