Table 4 Genotype and allele count of CHGB48 polymorphism in leprosy cases and healthy controls stratified by gender and adjusted by ethnicity and age.
From: Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy
Gender | Group | Genotype | HWE Test P | ||||
|---|---|---|---|---|---|---|---|
CC % | GC % | GG % | G % | C % | |||
Male | Leprosy (N = 92) | 15 (16.3) | 46 (50) | 31 (33.7) | 108 (58.7) | 76 (41.3) | 0.76 |
Control (N = 94) | 21 (22.3) | 37 (39.4) | 36 (38.3) | 109 (58.0) | 79 (42.0) | 0.06 | |
O R (95%CI) | 0.88 (0.3–2.5) | 2.85 (1.0–7.9) | 0.38 (0.16–0.9) | 0.99 (0.52–1.6) | 1.1 (0.67–1.8) | ||
P | 0.81 | 0.043 | 0.03 | 0.69 | |||
Female | CC % | GC % | GG % | G % | C % | ||
Leprosy (N = 48) | 10 (20.8) | 29 (60.4) | 9 (18.8) | 47 (48.9) | 49 (51.1) | 0.14 | |
Control (N = 96) | 22 (22.9) | 56 (58.3) | 18 (18.8) | 92 (47.9) | 100 (52.1) | 0.09 | |
O R (95%CI) | 0.7 (0.3–4.9) | 1.1 (0.3–3.1) | 0.77 (0.17–3.6) | 1.2 (0.65–2.4) | 0.832 (0.43–1.6) | ||
P | 0.623 | 0.916 | 0.739 | 0.579 | |||
Total | CC % | GC % | GG % | G % | C % | ||
Leprosy (N = 140) | 25 (17.9) | 75 (53.5) | 40 (28.6) | 155 (55.4) | 125 (44.6) | 0.32 | |
Control (N = 190) | 43 (22.6) | 93 (48.9) | 54 (28.5) | 201 (52.9) | 179 (47.1) | 0.86 | |
O R (95%CI) | 0.57 (0.3–1.1) | 1.67 (0.8–3.3) | 0.99 (0.48–2.3) | 1.05 (0.75–1.5) | 0.99 (0.7–1.4) | ||
P | 0.085 | 0.169 | 0.888 | 0.784 | |||
