Table 5 Genotype and allele count of CHGB23 polymorphism in leprosy cases and healthy controls stratified by gender and adjusted by ethnicity and age.
From: Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy
Gender | Group | Genotype | HWE test P | ||||
|---|---|---|---|---|---|---|---|
AG % | GG % | AA % | A % | G % | |||
Male | Leprosy (N = 96) | 44 (45.8) | 19 (19.8) | 33 (34.4) | 110 (57.3) | 82 (42.7) | 0.53 |
Control (N = 94) | 38 (40.4) | 14 (14.9) | 42 (44.7) | 122 (64.9) | 66 (35.1) | 0.27 | |
O R (95%CI) | 1.6 (0.8–3.3) | 1.72 (0.7–4.5) | 0.142 (0.22–0.93) | 0.087 (0.32–0.9) | 11.73 (1.1–2.9) | ||
P | 0.213 | 0.239 | 0.003 | 0.001 | |||
Female | AG % | GG % | AA % | A % | G % | ||
Leprosy (N = 49) | 31 (63.3) | 8 (16.3) | 10 (20.4) | 51 (52) | 47 (48) | 0.06 | |
Control (N = 95) | 50 (52.6) | 23 (24.2) | 22 (23.2) | 94 (49.5) | 96 (50.5) | 0.61 | |
O R (95%CI) | 1.82 (0.24–1.8) | 0.339 (0.46–4.9) | 0.46 (0.22–3.2) | 1.1 (0.61–1.8) | 0.917 (0.514–1.63) | ||
P | 0.263 | 0.573 | 0.671 | 0.768 | |||
Total | AG % | GG % | AA % | A % | G % | ||
Leprosy (N = 145) | 75 (51.7) | 27 (18.6) | 43 (29.7) | 161 (55.5) | 129 (44.5) | 0.57 | |
Control (N = 189) | 88 (46.6) | 37 (19.6) | 64 (33.9) | 216 (57.1) | 162 (42.9) | 0.50 | |
O R (95%CI) | 1.69 (0.35–1.0) | 0.79 (0.38–1.6) | 0.214 (0.22–0.85) | 0.747 (0.49–1.1) | 1.4 (0.99–2.10) | ||
P | 0.058 | 0.53 | 0.027 | 0.166 | |||
