Table 6 Genotype and allele count of C13orf31 polymorphism in multibacilary and paucibacilary patients stratified by gender and adjusted by ethnicity and age.
From: Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy
Gender | Clinical type | Genotype | ||||
|---|---|---|---|---|---|---|
AA (%) | GG (%) | AG % | A (%) | G (%) | ||
Male | Multibacillary (N = 38) | 14 (36.8) | 4 (10.5) | 20 (52.6) | 48 (63.2) | 28 (36.8) |
Paucibacillary (N = 22) | 9 (40.9) | 2 (9.1) | 11 (50) | 29 (65.9) | 15 (34.1) | |
OR (95%CI) | 0.34 (0.38–3.6) | 0.68 (0.1–4.8) | 0.91 (0.28–2.95) | 0.32 (0.5–2.6) | 1.75 (0.4–2) | |
P | 0.362 | 0.7 | 0.88 | 0.202 | ||
Female | Multibacillary (N = 12) | 2 (16.7) | 3 (25) | 7 (58.3) | 11 (45.8) | 13 (54.2) |
Paucibacillary (N = 12) | 9 (75) | 2 (16.7) | 1 (8.3) | 19 (79.2) | 5 (20.8) | |
OR (95%CI) | 0.034 (0.001–0.9) | 3.5 (0.08–14) | 16 (1.47–167) | 0.223 (0.06–0.8) | 4.5 (1.3–16) | |
P | 0.042 | 0.57 | 0.03 | 0.017 | ||
Total | Multibacillary (N = 50) | 16 (32) | 7 (14) | 27 (54) | 59 (59) | 41 (41) |
Paucibacillary (N = 34) | 18 (52.9) | 4 (11.8) | 12 (35.3) | 48 (70.6) | 20 (29.4) | |
OR (95%CI) | 0.93 (0.78–5.4) | 0.894 (0.38–6.6) | 0.97 (0.63–4.5) | 0.95 (0.81–3.3) | 1.1 (0.3–1.2) | |
P | 0.935 | 0.914 | 0.97 | 0.933 | ||
