Table 7 Genotype and allele count of C13orf31 polymorphism in leprosy and healthy people stratified by gender and adjusted by ethnicity and age.
From: Identification of novel genetic loci GAL3ST4 and CHGB involved in susceptibility to leprosy
Gender | Group | Genotype | HWE Test P | ||||
|---|---|---|---|---|---|---|---|
AA (%) | GG (%) | AG (%) | A (%) | G (%) | |||
Male | Leprosy (N = 60) | 23 (38.3) | 6 (10) | 31 (51.7) | 77 (64.2) | 43 (35.8) | 0.34 |
Control (N = 31) | 18 (58) | 2 (6.5) | 11 (35.5) | 47 (75.8) | 15 (24.2) | 0.86 | |
OR (95%CI) | 0.62 (0.8–5.4) | 2.5 (0.7–5.4) | 2.1 (0.1–4.9) | 0.9 (0.88–3.8) | 1.12 (0.28–1.2) | ||
P | 0.447 | 0.317 | 0.163 | 0.77 | |||
Female | Leprosy (N = 24) | 11 (45.8) | 5 (20.9) | 8 (33.3) | 30 (62.5) | 18 (37.5) | 0.16 |
Control (N = 49) | 29 (59.2) | 4 (8.2) | 16 (32.7) | 74 (75.5) | 24 (24.5) | 0.41 | |
OR (95%CI) | 1.5 (0.56–4.4) | 2.5 (0.07–1.3) | 2.14 (0.27–2.6) | 2.3 (0.2–1.2) | 1.3 (0.8–4) | ||
P | 0.429 | 0.06 | 0.217 | 0.54 | |||
Total | Leprosy (N = 84) | 34 (40.5) | 11 (13.1) | 39 (46.4) | 107 (63.7) | 61 (36.3) | 0.45 |
Control (N = 80) | 47 (58.8) | 6 (7.5) | 27 (33.7) | 121 (75.7) | 39 (24.3) | 0.45 | |
OR (95%CI) | 0.6 (0.25–1.1) | 3.3 (1.1–10) | 1.63 (0.78–3.4) | 0.56 (0.3–0.95) | 1.79 (1.1–3.1) | ||
P | 0.229 | 0.045 | 0.192 | 0.024 | |||
