Figure 4 | Scientific Reports

Figure 4

From: A novel bioreactor system for biaxial mechanical loading enhances the properties of tissue-engineered human cartilage

Figure 4

Chondrocyte viability and DNA content of GelMA-HAMA constructs. Viability of chondrocytes at (a) day 2 and (b) day 28 of free swelling culture, or (c) after 14 days of free swelling preculture and 14 days of intermittent biaxial mechanical stimulation at 30% compressive strain and 1 mm shear amplitude (1 Hz, 1 h daily). Living cells appear green, while dead cells appear red. (d) Quantified viability (3 donors, 1 construct each) and (e) total DNA content (3 donors, 2 constructs each) of free swelling (FS) and loaded (L) constructs. Stars indicate a statistical difference between constructs at day 2 and day 28 of culture (*p < 0.05, **p < 0.01).

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