Table 1 Overview of 70 significant DEGs comparing rapid and slow groups (q-value < 0.05).
Up-regulated DEGs in the rapid group | |||
|---|---|---|---|
Gene Symbol | Full Name | Fold Change | q-value |
COL1A1 | collagen type I alpha 1 chain | 6.52 | 2.62E-20 |
COL3A1 | collagen type III alpha 1 chain | 5.35 | 1.05E-17 |
COL1A2 | collagen type I alpha 2 chain | 4.01 | 4.66E-13 |
COL5A1 | collagen type V alpha 1 chain | 3.8 | 7.21E-05 |
COL6A3 | collagen type VI alpha 3 chain | 3.27 | 7.08E-07 |
COL6A1 | collagen type VI alpha 1 chain | 3.26 | 1.82E-05 |
LOX | lysyl oxidase | 3.13 | 1.42E-03 |
COL6A2 | collagen type VI alpha 2 chain | 3.07 | 2.34E-04 |
PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 2.99 | 5.76E-03 |
CDCA8 | cell division cycle associated 8 | 2.98 | 2.80E-02 |
COL11A1 | collagen type I alpha 1 chain | 2.86 | 5.33E-03 |
COL15A1 | collagen type XI alpha 1 chain | 2.82 | 6.24E-03 |
C1QTNF6 | C1q and tumor necrosis factor related protein 6 | 2.81 | 4.98E-03 |
FNDC1 | fibronectin type III domain containing 1 | 2.81 | 3.22E-02 |
FN1 | fibronectin 1 | 2.8 | 4.10E-02 |
CCDC80 | coiled-coil domain containing 80 | 2.72 | 7.98E-04 |
MFSD7 | major facilitator superfamily domain containing 7 | 2.7 | 3.22E-02 |
FBLN1 | fibulin 1 | 2.69 | 4.10E-02 |
NID2 | nidogen 2 | 2.61 | 1.52E-07 |
COL4A2 | collagen type IV alpha 2 chain | 2.6 | 1.42E-03 |
FAM69B | family with sequence similarity 69, member B | 2.6 | 3.42E-02 |
NDN | necdin | 2.59 | 4.39E-02 |
COL4A1 | collagen type I alpha 1 chain | 2.59 | 5.76E-03 |
HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled | 2.58 | 2.60E-02 |
PCOLCE | procollagen C-endopeptidase enhancer | 2.58 | 5.83E-03 |
OLFML2B | olfactomedin like 2B | 2.56 | 6.24E-03 |
TK1a | Thymidine kinase 1 | 2.49 | 1.98E-02 |
C15orf39 | chromosome 15 open reading frame 39 | 2.47 | 2.76E-02 |
RCN3 | reticulocalbin 3 | 2.46 | 6.94E-04 |
MFAP2 | microfibrillar associated protein 2 | 2.45 | 1.42E-03 |
HSPG2 | perlecan | 2.45 | 1.20E-02 |
PRSS35 | protease, serine 35 | 2.45 | 4.10E-02 |
MMP2 | matrix metallopeptidase 2 | 2.43 | 4.48E-05 |
FBN1 | fibrillin 1 | 2.37 | 3.57E-03 |
CD248 | CD248 molecule | 2.36 | 2.72E-02 |
FOXRED2 | FAD dependent oxidoreductase domain containing 2 | 2.35 | 1.11E-02 |
GXYLT2 | glucoside xylosyltransferase 2 | 2.34 | 3.62E-02 |
FSCN1 | fascin actin-bundling protein 1 | 2.34 | 1.20E-02 |
ENSCAFG00000008741b | novel gene | 2.29 | 1.18E-02 |
ENSCAFG00000012963b | novel gene | 2.28 | 1.23E-03 |
BGN | biglycan | 2.19 | 1.85E-02 |
FAS | Fas (TNF receptor superfamily member 6) | 2.16 | 2.08E-02 |
ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2 | 2.15 | 3.23E-02 |
PXDN | peroxidasin | 2.14 | 4.10E-02 |
SPARC | secreted protein acidic and cysteine rich | 2.13 | 4.48E-05 |
THBS1 | thrombospondin 1 | 2.12 | 1.26E-04 |
KCP | kielin/chordin-like protein | 2.12 | 4.19E-02 |
LRP1 | LDL receptor related protein 1 | 2.11 | 7.98E-04 |
CERCAM | cerebral endothelial cell adhesion molecule | 2.11 | 4.39E-02 |
ITGA5 | integrin subunit alpha 5 | 2.07 | 7.03E-03 |
BMP1 | bone Morphogenetic Protein 1 | 1.88 | 6.74E-05 |
FSTL1 | follistatin Like 1 | 1.72 | 1.25E-05 |
PTGFRN | prostaglandin F2 Receptor Inhibitor | 1.66 | 2.61E-05 |
Down-regulated DEGs in the rapid group | |||
UGT1A6 | UDP glucuronosyltransferase family 1 member A6 | −4.77 | 1.23E-03 |
NAT8 | N-acetyltransferase 8 (putative) | −4.1 | 1.09E-04 |
R3HDML | R3H domain containing like | −4.02 | 1.42E-03 |
LIX1 | limb and CNS expressed 1 | −3.83 | 7.21E-03 |
PRLR | prolactin receptor | −3.73 | 4.64E-04 |
SCD5c | stearoyl-CoA desaturase 5 | −3.55 | 1.07E-05 |
FMO2 | flavin containing monooxygenase 2 | −3.42 | 1.78E-02 |
OAT3/SLC22A8 | solute carrier family 22 member 8 | −3.37 | 2.45E-02 |
SI | sucrase-isomaltase | −3.25 | 1.16E-02 |
ENSCAFG00000003760b | novel gene | −2.92 | 3.96E-02 |
SLC26A4 | solute carrier family 26 member 4 | −2.79 | 7.14E-03 |
ENSCAFG00000000799b | novel gene | −2.77 | 3.25E-02 |
HEPACAM2 | HEPACAM family member 2 | −2.66 | 8.81E-03 |
IDO2 | indoleamine 2,3-dioxygenase 2 | −2.58 | 3.42E-02 |
PECR | peroxisomal trans-2-enoyl-CoA reductase | −2.57 | 6.24E-03 |
MT-ND3 | mitochondrially encoded NADH dehydrogenase 3 | −2.16 | 3.49E-03 |
ABCA4 | retinal-specific ATP-binding cassette transporter | −1.91 | 1.08E-04 |