Figure 1 | Scientific Reports

Figure 1

From: Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression

Figure 1

Microarray analysis identifies disparate transcriptional responses to ALDH1A3 manipulation and atRA treatment in MDA-MB-231 and MDA-MB-468 cells. (a) Overlap of ALDH1A3-upregulated genes in MDA-MB-231 (ALDH1A3 cDNA/scramble vector) compared to MDA-MB-468 (scramble vector/ALDH1A3 shRNA knockdown). (b) Overlap of genes upregulated by 100 nM atRA in MDA-MB-231 and MDA-MB-468. Comparison of ALDH1A3-upregulated and atRA-upregulated genes in (c) MDA-MB-231 and (d) MDA-MB-468). (e) Sequence logos generated from all RAREs identified in associated gene lists.

Back to article page