Table 4 Genotype and allele associations of TG-PCA3 STR with Gleason scores.

From: A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness

Genotype

GS <8

GS ≥8

OR (95% CI)a

P-valuea

OR (95% CI)b

P-valueb

P-valuec

P-valued

P-valuee

P-valuef

10/10

2 (0.2)

0

—

—

—

—

—

—

—

—

10/11

2 (0.2)

0

—

—

—

—

—

—

—

—

10/12

2 (0.2)

1 (0.7)

—

—

—

—

—

—

—

—

11/9

0

1 (0.7)

—

—

—

—

—

—

—

—

11/11

534 (58)

86 (59)

Reference

—

—

—

—

—

—

—

11/12

309 (34)

52 (36)

—

ns

—

—

—

—

—

—

11/13

2 (0.2)

0

—

—

—

—

—

—

—

—

12/12

64 (7)

5 (3)

—

ns

—

—

—

—

—

—

12/13

1 (0.1)

0

—

—

—

—

—

—

—

—

Allele

9

0

1 (0.3)

—

—

—

—

—

—

—

—

10

8 (0. 4)

1 (0.3)

—

—

—

—

—

—

—

—

11

1381 (75)

225 (78)

2.00 (1.06–3.76)

0.031

2.33 (1.16–4.67)

0.01

0.017.

0.01.

0.02

0.007

12

440 (24)

63 (22)

—

ns

—

—

—

—

—

—

13

3 (0.2)

0

—

—

—

—

—

—

—

—

  1. Calculated using abinary logistic regression, bage corrected binary logistic regression, cbootstrap (two-tailed), dbootstrap (two-tailed) age corrected, efamily history corrected binary logistic regression, fbootstrap (two-tailed) family history corrected. The 11/11 repeats was used as reference for genotype analysis (IBM SPSS Statistic Processor; 23). GS: Gleason score; ns: no significant: CI: confidence interval.
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