Figure 5 | Scientific Reports

Figure 5

From: CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway

Figure 5The alt text for this image may have been generated using AI.

CSA13 did not affect cell viability and cell migration of fibroblasts. (A) Human CCD18Co fibroblasts were transiently transfected with control or FPRL1 siRNA overnight, followed by CSA13 for 24 hours. Each PCR array (Human Fibrosis PAHS120ZE-4, Qiagen, CA) detects 84 genes. Only CSA13-dependent genes are shown here. (B) The CCD-18Co fibroblasts were treated with CSA13 for 24 hours. The cell viability was determined by MTS assay at 490 nm. (C) The 3T3 fibroblasts were treated with CSA13 for 72 hours. The scratch gaps were recorded at 100X magnification. The results are representative of 3 experiments.

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