Table 1 Comparison of results with each plan.

From: Comparison of graphical optimization or IPSA for improving brachytheraphy plans associated with inadequate target coverage for cervical cancer

parameters

GrO

IPSA1

IPSA2

IPSA1-0

IPSA2-0

p value

D100(Gy)

3.2 ± 0.5

3.1 ± 0.6

3.5 ± 0.5a,c,d

3.4 ± 0.5a,c,d

3.6 ± 0.5a,b,c

0.042

D90(Gy)

5.2 ± 0.6

5.0 ± 0.6e

5.4 ± 0.6a

5.2 ± 0.6b,d

5.4 ± 0.6a

0.038

V100(%)

66.2 ± 8.8

62.7 ± 9.7e

68.0 ± 9.4a

65.9 ± 8.8b,d

68.8 ± 9.2a

0.036

V150(%)

35.9 ± 5.8

33.4 ± 6.7e

35.8 ± 5.6

34.7 ± 5.5e

36.2 ± 5.6

0.022

V200(%)

21.9 ± 3.5

19.6 ± 3.7e

21.4 ± 3.4

20.7 ± 3.5e

21.7 ± 3.4

0.041

CNI

0.62 ± 0.08e

0.57 ± 0.09e

0.59 ± 0.09

0.58 ± 0.08

0.60 ± 0.09

0.042

CI

0.94 ± 0.06e

0.91 ± 0.04e

0.87 ± 0.06

0.89 ± 0.04e

0.87 ± 0.06

0.016

Bladder2cc(Gy)

4.4 ± 0.1e

4.5 ± 0.03

4.5 ± 0.07

4.5 ± 0.04

4.5 ± 0.08

0.027

Rectum2cc(Gy)

3.6 ± 0.4

3.4 ± 0.4e

3.5 ± 0.4

3.5 ± 0.4

3.6 ± 0.4

0.044

Sigmoid2cc(Gy)

2.7 ± 1.0

2.5 ± 0.9

2.7 ± 1.0

2.7 ± 1.0

2.8 ± 1.0

0.653

Total dwell time(s)

587.1 ± 304.9e

565.1 ± 289.4e

632.0 ± 324.8

602.7 ± 305.5e

643.0 ± 330.3

0.002

Max dwell time(s)

54.2 ± 66.9

50.8 ± 35.5

68.0 ± 35.5

111.8 ± 75.4e

74.2 ± 53.1

0.000

SD of dwell time (s)

12.6 ± 13.7

13.3 ± 9.2

18.0 ± 15.3a,c

22.8 ± 14.7e

19.0 ± 13.2a,c

0.003

  1. Results are mean ± 1 standard deviation.
  2. aSignificantly different from the GrO.
  3. bSignificantly different from the IPSA2.
  4. cSignificantly different from the IPSA1.
  5. dSignificantly different from the IPSA2-0.
  6. eSignificantly different from all other plans.