Table 3 PD-L1 IHC scoring according to the SP142-IHC assay scoring algorithm.

From: Assessment of Concordance between 22C3 and SP142 Immunohistochemistry Assays regarding PD-L1 Expression in Non-Small Cell Lung Cancer

  

SP142-IHC assay

Total

Kappa value P value

McNemar-Bowker

0

1+

2+

3+

22C3-IHC assay

0

40

5

0

0

45

0.481P < 0.001

P < 0.001

1+

21

15

0

0

36

2+

9

11

5

1

26

3+

4

6

9

9

28

Total

74

37

14

10

135

  1. 0 indicates negative, 1+ weakly positive, 2+ moderately positive, and 3+ strongly positive PD-L1 expression.
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