Figure 7
From: Cell-Free DNA Kinetics in a Pre-Clinical Model of Head and Neck Cancer
Plasma ctDNA levels in the setting of tumour recurrence and lymph node swelling. Data from Rabbit 6 (a,c,e) and Rabbit 8 (b,d,f) are shown. (a,b) Plots showing primary tumour (blue) and lymph node (red) volumes, as well as the plasma ctDNA (full green circles) and total plasma DNA (open green circles) concentrations at the indicated post-operative days. (c,d) Axial and sagittal orientation serial CT images of primary tumour (yellow boxes) and lymph node (green boxes) over time course at the indicated post-operative days. (e,f) Low- and high-magnification histology images of pan-cytokeratin staining for recurrent primary tumour and lymph node tissue from endpoint dissection.
