Table 2 Analysis of SNPs related to haplogroup D4 and H in 4 clusters※.

From: Mitochondrial DNA Mutations Associated with Type 2 Diabetes Mellitus in Chinese Uyghur Population

SNP

haplogroup

Region

AA change

OR

95% CI

Adjusted P-value*

2706A1

H

16S RNA

 

6.49

1.89–22.33

0.004172

3010A2

D4

16S RNA

 

5.94

1.52–23.18

0.03624

7028C1

H

MT-CO1

 

8.71

2.40–31.55

0.0008832

8414T2

D4

MT-ATP8

L17F

5.94

1.52–23.18

0.03624

14668T2

D4

MT-ND6

 

5.94

1.52–23.18

0.03624

  1. ※m.8414 T were nonsynonymous. Other 2 SNPs (m.2706 A, m.3010 A) from haplogroup H and D4 might change the structure of mitochondrial 16S RNA. AA: amino acid. Symbol *indicated that adjusted P-values were corrected by Bonferroni correction. Superscript in the first column indicated a specific cluster that a specific SNP belonged to.