Table 1 Description of study populations.

From: From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function

Study

QMDiab

GCKD

Health status

Non-CKD individuals

CKD patients

Ancestry

Arab/Asian

European

Population size

N

111

382

Sex, male

N (%)

46 (41%)

235 (62%)

Age, years

Mean (SD)

38.3 (11.6)

59.5 (12.0)

Body mass index, kg/m²

Mean (SD)

28.3 (5.1)

30.1 (5.9)

Blood measures*

- Creatinine, mg/dL

Mean (SD)

0.80 (0.18)

1.47 (0.43)

- Cystatin C, mg/L

Mean (SD)

NA

1.54 (0.42)

eGFR CKD-EPI, mL/min/1.73 m²

- based on creatinine

Mean (SD)

104.0 (15.7)

50.9 (17.6)

- based on cystatin C

Mean (SD)

NA

47.6 (17.0)

Urine measures*

- Creatinine, mg/dL

Mean (SD)

139.2 (84.4)

78.7 (52.9)

- UACR, mg/g

Median (IQR)

NA

62.5 (11.9–450.4)

  1. *Creatinine in both blood (serum in GCKD and plasma for QMDiab) and urine were measured using a calibrated, enzymatic, standard clinical laboratory assay. Creatinine conversion: 1 mg/dL = 88.4 µmol/L. IQR – interquartile range; NA – not available.
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