Figure 6
Oxidative demethylation of ketones and alcohols. The reactions were performed after pre-treatment of I2 (3 eq.) and t-BuOK (9 eq.), using 3 eq. of H2O at room temperature for 1 h (same as the conditions in Table 1, entry 5). Isolated yields. (1H NMR yields are shown in parentheses). aIsolated yields after benzylation. bThe endo:exo ratio was unchanged during the course of reaction, as determined by 1H NMR measurements. c t-BuOK (10 eq.) and I2 (4 eq.) were used.
