Table 8 Pathways identified by IPA to be associated with proteins encoded by mutated genes in COA/UAB-6.
From: Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors
Pathways affected by variant gene products | p-value | Ratio |
|---|---|---|
Eicosanoid signaling | 0.000989 | 2/63 (0.032) |
Prostanoid biosynthesis | 0.0067 | 1/9 (0.111) |
Protein kinase A signaling | 0.0253 | 1/386 (0.003) |