Table 8 Pathways identified by IPA to be associated with proteins encoded by mutated genes in COA/UAB-6.

From: Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors

Pathways affected by variant gene products

p-value

Ratio

Eicosanoid signaling

0.000989

2/63 (0.032)

Prostanoid biosynthesis

0.0067

1/9 (0.111)

Protein kinase A signaling

0.0253

1/386 (0.003)