Figure 3

Evaluation of CEA, CA19-9, CRP and leucocyte count as prognostic marker for CCA patients after tumor resection. Using our optimal prognostic cut-off value, Kaplan-Meier curve analysis shows highly significant impaired long-term survival for patients with a CA19-9 serum level above 324.15 U/ml (a), a CEA serum level above 4.55 µg/l (b) and a CRP level above 7.7 mg/L (c), respectively. The ideal cut-off value for the leucocyte count of 8.2 cells/nl is unable to discriminate long-term survivors and non-survivors (d).