Figure 4 | Scientific Reports

Figure 4

From: Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide

Figure 4

The stability of the complexes in challenging environments. (a) Transfection efficacy is assessed after DNase I treatment. The particles are formed at N/P2, digested with DNase and used for the transfection in CHO cells. jetPEI was formed at N/P8. (b) The stability of the complexes against proteinase K was evaluated by plotting the amount of accessible pDNA in time (assessed with fluorescent DNA intercalating dye). The peptide complexes were formed at N/P2 (unless indicated otherwise), jetPEI was formed at N/P8.

Back to article page