Figure 2

Growth kinetics of rDENV4/3. (A) DENV3, DENV4, DENV4 M12, DENV4 M14, and DENV4 M16 were used to perform multi-step growth curves on Vero-81 (A) and C6/36 (B) cells. Infectious titers are presented as ffu/ml in the cell culture supernatant at the indicated time point post-infection. Examples of foci for the same virus panel on Vero (C) or C6/36 (D) cells.