Figure 3

Gain of binding and neutralization of hmAb 5J7 on rDENV4/3. (A) ELISA binding curves for DENV3-specific hmAb 5J7 on DENV3, DENV4, DENV4 M12, DENV4 M14, and DENV4 M16. Neutralization assays on Vero-81 (B) and U937-DC-SIGN (C) for DENV3, DENV4, DENV4 M12, M14, and M16. Error bars represent the range of values. Graphs show one representative experiment of at least 2 independent experiments.