Figure 3 | Scientific Reports

Figure 3

From: A Multimodal Biomicroscopic System based on High-frequency Acoustic Radiation Force Impulse and Multispectral Imaging Techniques for Tumor Characterization Ex vivo

Figure 3

Multimodal imaging of colorectal tumors ex vivo using the proposed system. (a) Multispectral images obtained at the indicated wavelengths. (b) Normalized spectral signatures of colorectal tumors and normal colon tissues. (c) Multispectral classified image. The black dotted arrow indicates the scanning line. (d) A high-frequency B-mode image. (e) A high-frequency ARFI image overlaid with the corresponding B-mode image. (f) H&E stained image corresponding to the B-mode and ARFI image. The red arrows indicate tumor regions. (g) Three-dimensional B-mode and (f) ARFI image (2 mm × 2.8 mm × 4 mm in x, y, and depth). The pseudo-colored map indicates tissue displacements.

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