Table 2 Common lipids between multivariate analysis (SIMCA® and biosigner analysis) performed on ALS patients and mice models of ALS. Lipids in bold: identified in patients and mice, and in italic: structures found in lipids common to patients and mice.

From: Lipidomics Reveals Cerebrospinal-Fluid Signatures of ALS

Lipid groups

ALS patients

ALS model mice

Examples of common structures

LysoPC

 

C16:0, C17:0, C18:2, C20:3, C20:4, C18:1

PC

C30:0, C32:2p and e, C35:4, C36:2p, C36:4p, C37:5,C40:4, C40:6p and e, MePC(37:1)

C32:0, C32:1, C32:2p, C34:1, C34:2, C36:1, C36:2e, C36:4p, C36:5, C38:0, C38:4, C38:5, C38:6, C40:6e

SM

C34:2, C34:0, C36:0, C39:1, C36:1, C43:2

C16:0, C18:0, C18:1, C24:1