Table 4 Association between FGB 455 G/A polymorphism and risk of CES in AF patients.

From: The β-fibrinogen gene 455G/A polymorphism associated with cardioembolic stroke in atrial fibrillation with low CHA2DS2-VaSc score

Genetic model

Crude OR (95% CI)*

P

Adjusted OR (95% CI)**

Adjusted P

P Bonferroni

Additive model

1.452(1.183,1.783)

<0.001

1.548(1.251–1.915)

<0.001

0.001

Dominant model

1.481(1.154–1.900)

0.002

1.588(1.226–2.057)

<0.001

0.003

Recessive model

2.163(1.245–3.758)

0.006

2.394(1.357–4.223)

0.003

0.015

  1. *Crude ORs were calculate by univariate logistic regression analysis. **Adjusted ORs were obtained from multivariate logistic regression additionally adjusted by age, sex, BMI, smoking, drinking, hypertension, diabetes mellitus, heart failure, vascular disease, LAD, AF type, LDL, and CRP. Additive model (AA vs. GA vs. GG). Dominant model (AA + GA vs. GG). Recessive model (AA vs. GA + GG). OR: odds ratio; CI: confidence interval.
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