Figure 3 | Scientific Reports

Figure 3

From: Comprehensive Expression Analysis of microRNAs and mRNAs in Synovial Tissue from a Mouse Model of Early Post-Traumatic Osteoarthritis

Figure 3

miRNA and mRNA microarray expression profiling of synovial tissue from male mice. MA plots displaying average log-expression intensity values and log2 fold change for each miRNA expressed between DMM and sham in (A) 1 week synovium and (B) 6 week synovium. MA plots displaying average log-expression intensity values and log2 fold change for each mRNA transcript expressed between DMM and sham in (C) 1 week synovium and (D) 6 week synovium. Volcano plots showing differential (E) miRNA expression and (F) mRNA expression in synovium of 6 week compared with 1 week post-surgery samples. Blue dots represent miRNA/mRNA down regulated >2 fold with adjusted p value < 0.05, green dots represent miRNA/mRNA with adjusted p value < 0.05 and log2 fold change between -1 and 1, red dots represent miRNA/mRNA up regulated >2 fold and adjusted p value < 0.05 and grey dots represent non-significant entities.

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