Figure 6

Ingenuity pathway-generated core functional analysis of the 394 differentially expressed synovial miRNAs between 1 and 6 weeks post-surgery (adj.p.val < 0.05). Most significant (A) disease and disorders, (B) molecular and cellular functions and (C) physiological system development and function mapped to the network of dysregulated miRNAs. Threshold bar shows cut-off point of significance p < 0.05, −log(P-value) of 1.3 using Fisher’s exact test.