Table 1 Ancient and current traditional medicinal uses of Muricidae opercula.

From: Volatile and bioactive compounds in opercula from Muricidae molluscs supports their use in ceremonial incense and traditional medicines

Country/Ancient Scholar

Source species#

Preparation

Pharmaceutical properties (Treatment/curing)

Reference

Ancient Greece/Dioscorides and Galen

Hexaplex trunculus, Bolinus (Murex) brandaris, Stramonita (Thais) haemastoma

Crushed and mixed with oil and vinegar

Hearing loss, swollen spleen, depression, menstrual cycle abnormalities and after labour for placenta removal

24

Medieval Eastern Mediterranean Genizah

Chicoreus virgineus (Murex anguliferu)

Blatta byzantine Opercula drug

Rheumatism or arthritis, stomach ulcer, skin diseases, teeth problems, eye and ear diseases, tumors, epilepsy, paralysis, purgative and treatment of uterine diseases.

25

Kingdom of Bahrein. Ahmad Ibn Muhammad al-Ghafiqi

Chicoreus ramosus (Murex inflatus)

Fumigation. Smell the smoke produced while placing the operculum on slowly burning charcoal.

Atresia of the uterus

18,20

Central Europe and Middle East

Hexaplex trunculus

1) Fumigation. 2) Ashes of opercula. 3) Operculum medicine (Blatta byzantine) mixed with vinegar.

1) Dislodge the placenta after labour. 2) Wound healing. 3) Reduced swollen spleen

18,54

Chinese traditional medicine

Rapana bezoar

Decoct* the operculum (10–20 g) and ingest; Ustulate$ the shell, grind into powder and apply externally.

Clear heat, expel toxins, remove dampness through diuresis, used to treat strangury (painful & frequent urination), swelling and ulcers on the body surface, hepatic coma, eye diseases and dysentery.

50,66

Southern India ancient Sanskrit medical texts

Muricidae opercula

“Nakhi” used in incense and medicinal oil heated in clarified butter or cooked with honey

Destroys poison, destroys certain types of skin diseases, remove phlegm. When used in incense it is said to be like a “prostitute” or “market place charmer”

8

Modern India

Muricidae opercula

Opercula oil “Choya Nakh”. Dry distillation of the roasted opercula mixed with a base oil, usually cedarwood oil

Mix a few drops of opercula oil with other incense ingredients. Inhalation of incense smoke to cure stomach pain, liver ailments, epilepsy and irregular menses.

74,75

  1. #Accepted names are provided according to the World Register of Marine Species76 with the alternative names in the original source in brackets, *decoct is to extract by boiling; $ustulate is to blacken or scorch.