Figure 2 | Scientific Reports

Figure 2

From: Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment

Figure 2

Populations and phenotypes of macrophages derived from MMTV-WNT + breast tumours. (A) Representative flow cytometry plots showing gating of CD11b+CD45+ cells in MMTV-WNT+ tumours. (B) Analysis of the percentage of CD45+ cells which are CD11b+ or CD11b-. (C) Different populations of CD11b+ CD45+ cells. (D) Percentage of CD206+ (M2) or CD86+ (M1) macrophages obtained from CD11c-F480int macrophages from breast tumours on MMTV mice or mammary fat pads of B6 control female mice. Data shown are mean ± SD (n = 4). *P ≤ 0.05, **P ≤ 0.01, ANOVA.

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