Table 3 Subgroup analysis for the incidence of CA-AKI on the baseline chloride level depending on serum creatinine level [‘Normal Cr group’ (n = 12,280) and ‘Slightly increased Cr group (n = 808)].

From: Baseline Chloride Levels are Associated with the Incidence of Contrast-Associated Acute Kidney Injury

Variables

Univariate

Multivariate

RR (95% CI)

P-value

RR (95% CI)

P-value

Normal Cr group (n = 12,280)

 Normochloremia

Reference

 

Reference

 

 Hypochloremia

1.347 (1.086–1.671)

0.007

1.314 (1.550–1.636)

0.015

 Hyperchloremia

2.356 (1.419–3.913)

0.001

1.360 (0.799–2.315)

0.257

Slightly increased Cr group (n = 808)

 Normochloremia

Reference

 

Reference

 

 Hypochloremia

1.781 (1.048–3.027)

0.033

1.641 (0.940–2.866)

0.082

 Hyperchloremia

2.303 (0.912–5.819)

0.078

2.322 (0.872–6.186)

0.092

  1. Abbreviations; CA-AKI, contrast-associated acute kidney injury; RR, relative risk; CI, confidence interval; Cr, creatinine.
  2. Adjusted for age, sex, admission status, comorbidity diseases including DM, hypertension, coronary artery disease, and heart failure, serum creatinine level, serum BUN level, serum tCO2.
  3. Normal Cr group; patients who had a serum Cr level of less than 1.2 mg/dL.
  4. Slightly increased Cr group; patients who had 1.2 ≤ serum Cr levels < 2.0 mg/dL.
  5. Hypochloremia; chloride level less than 98 mEq/L at baseline.
  6. Normochloremia; chloride level between 98 to 110 mEq/L at baseline.
  7. Hyperchloremia; chloride level over 110 mEq/L at baseline.
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