Figure 2 | Scientific Reports

Figure 2

From: Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference

Figure 2

RNAscope in situ hybridization using CB2R and tyrosine hydroxylase probes in DAT-Cnr2 mice (a,b). (a) RNAscope in situ hybridization of mouse VTA section, red color represents tyrosine hydroxylase (TH) mRNA, green CB2R mRNA and blue DAPI nucleus staining. Genotypes of Cnr2-floxed and DAT-Cre are marked with white color on the upper left corners of the sections. White arrow heads represent colocalization of CB2R mRNA and TH mRNA; green arrow heads CB2R mRNA localization in TH negative cell types and orange arrow heads TH positive neurons without CB2R mRNA. (b) Spleen section as positive control of CB2R mRNA level that is more abundant in immune cells.

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