Figure 9
From: Cell Cycle Model System for Advancing Cancer Biomarker Research
Detection propensity for the list of 352 cancer marker proteins. (a) Bar graph displaying enriched GO cellular compartments. Only categories with >2-fold enrichment and FDR <6% are shown. Labels on the right of each bar indicate the number of proteins that matched that particular category. Enrichment status was assessed with DAVID tools. (b) Venn diagram displaying the overlap between cancer marker proteins associated with the plasma membrane/cell surface, the exosome/extracellular space, and the proteins that have been previously identified in blood or plasma. (c) Biological processes and pathways represented by exosome proteins.
