Figure 6
From: GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity
The structure of GSTO1-1 with ML175. (A) stereo-diagram showing the model of GSTO1-1 with ML175 bound to C32. ML175 (grey carbon atoms) and surrounding residues (green carbon atoms) are represented in stick form. The backbone of the protein is represented in cartoon form. (b) Stereo-diagram showing the active site of GSTO1-1 in complex with ML175 (green) and GSH (purple) superposed. (c) stereo diagram showing the active site of GSTO1-1 in complex with ML175 (green) and C1-27 (purple) superposed. The backbones of the proteins are represented in cartoon form.
