Table 2 Comparison of lymph node positive vs. lymph node negative patients.

From: Preoperative neutrophil-to-lymphocyte ratio and tumor-related factors to predict lymph node metastasis in nonfunctioning pancreatic neuroendocrine tumors

Variables

Lymph node negative

Lymph node positive

Univariable analysis

(n = 74)

(n = 27)

P

Age (years)

  

0.107

 ≤60

56

16

 

 >60

18

11

 

Gender

  

0.94

 Female

35

13

 

 Male

39

14

 

Symptomatic diagnosis

  

0.003

 No

32

3

 

 Yes

42

24

 

Albumin (g/l)

  

0.566

 <35

5

1

 

 ≥35

69

26

 

AKT (U/l)

  

0.001

 <183

71

20

 

 ≥183

3

7

 

NLR

  

<0.001

 <1.80

36

3

 

 ≥1.80

38

24

 

LMR

  

0.01

 <3.92

28

18

 

 ≥3.92

46

9

 

PLR

  

0.025

 <168.25

62

17

 

 ≥168.25

12

10

 

CA199

  

0.137

 Normal

68

22

 

 Abnormal

6

5

 

CA125

  

0.473

 Normal

69

24

 

 Abnormal

5

3

 

CEA

  

0.283

 Normal

72

25

 

 Abnormal

2

2

 

AFP

  

0.727

 Normal

70

26

 

 Abnormal

4

1

 

ECOG-PS

   

 0,1

68

23

0.318

 ≥2

6

4

 

Tumor size (cm)

  

0.005

 <2.5

18

0

 

 ≥2.5

56

27

 

Tumor location

  

0.055

 Head/uncinate/neck

28

16

 

 Body/tail

46

11

 

Distant metastasis

  

0.208

 No

65

21

 

 Yes

9

6

 

Ki-67 index

  

0.001

 ≤2%

27

1

 

 3 to 20%

37

15

 

 >20%

10

11

 

Vascular invasion

  

0.012

 No

67

19

 

 Yes

7

8

 
  1. AKT, alkaline phosphatase; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio; CA199, carbohydrate antigen 199; CEA, carcinoembryonic antigen; AFP, alpha-fetoprotein; CA125, carbohydrate antigen 125; ECOG-PS, Eastern Cooperative Oncology Group performance status. P-value < 0.05 marked in bold font shows statistical significant.
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