Figure 4 | Scientific Reports

Figure 4

From: Single, very low rituximab doses in healthy volunteers - a pilot and a randomized trial: implications for dosing and biosimilarity testing

Figure 4

A pharmacokinetic model: plasma rituximab concentrations with different dosing regimens. Arrows indicate infusions of rituximab. Data were adapted from Cohen et al.30 2 × 1000 mg (day 1 and day 15), Iacona et al.3 4 × 375 mg/m2/week and extrapolated from data of this trial (1 mg/m2 and 2 × 100 mg (smallest vial size)).

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