Table 3 Frequencies of S267F variant of NTCP in patients with chronic hepatitis B, cirrhosis, and HCC.

From: Effect of S267F variant of NTCP on the patients with chronic hepatitis B

Polymorphism

CHB only

CHB + LC

CHB + HCC

CHB vs. LC

CHB vs. HCC

LC vs. HCC

n = 549

n = 333

n = 318

P

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

S267F

CC

531 (96.7)

330 (99.1)

307 (96.5)

1.000

 

1.000

 

1.000

 

CT

18 (3.3)

3 (0.9)

11 (3.5)

0.036

0.268 (0.078–0.917)

0.887

0.946 (0.441–2.029)

0.037

0.254 (0.070–0.918)

  1. Data are expressed as n (%). CHB, chronic hepatitis B; LC, liver cirrhosis, HCC, hepatocellular carcinoma; OR, odds ratio; 95% CI, 95% confidence interval.
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