Figure 6
From: Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives
Inhibition assays of estradiol disulfate on KAT. (a) Inhibitory activity of estradiol disulfate in a dose-dependent format on KAT-I (IC50: 291.5 (±19.6) μM, R2 = 0.95). (b) Inhibitory activity of estradiol disulfate in a dose-dependent format on KAT-II (IC50: 26.3 (±1.4) μM, R2 = 0.98). Both plots used data from at least 3 sets of tests. Diagrams were produced using GraphPad Prism v7.0259.
