Figure 6 | Scientific Reports

Figure 6

From: Runx2 mediated Induction of Novel Targets ST2 and Runx3 Leads to Cooperative Regulation of Hypertrophic Differentiation in ATDC5 Chondrocytes

Figure 6

Hypertrophic zone reduction in ST2−/− mice. The H&E staining of femur (A) and tibial bones (B) of 5 week old WT (upper panels, left and right) and ST2−/− (lower panels, left and right) mice. The magnifications are 2,5x with scale bar of 500 µm and 10x with scale bar of 100 µm. (C) The graphs represent % of femur and tibial proliferative and hypertrophic zones relative to the respective femur/tibia full length in WT and ST2−/− mice at the age of 3 and 5 weeks old. For the size measurement, several randomly selected fields from 3 WT (6 tibias and 6 femurs) and 3 ST2−/− (5 tibias and 5 femurs) mice were analyzed. PZ, proliferative zone and HZ, hypertrophic zone.

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