Figure 1
From: TRPV1 enhances the afferent response to P2X receptor activation in the mouse urinary bladder
Bladder afferent nerves respond to αβMe-ATP. (a) Experimental trace of afferent nerve activity in response to increasing concentrations of αβMe-ATP applied for 60 s before washout; (b) concentration-response curve of afferent nerve activity to αβMe-ATP; (c) concentration-response curve of intravesical pressure (contraction) to αβMe-ATP; (d) afferent nerve and intravesical pressure responses to repeat applications of αβMe-ATP (30 µM); (e) afferent nerve time course response to repeated applications of αβMe-ATP (30 µM) applied for 60 s before washout; (f) peak afferent firing in response to repeat application of αβMe-ATP (30 µM). Data shown are mean ± SEM (n = 9).
