Table 2 Differential abundance analysis results on public clonotypes.

From: Deep sequencing of blood and gut T-cell receptor β-chains reveals gluten-induced immune signatures in celiac disease

  

DA clonotypes in:

Repertoire type

No. of Clonotypes (RP Pvalue < 0.01)+

No. of DA clonotypes (SFS Accuracy > = 0.75)*

Sorted

Total CDPBMC

CDPBMC 0

CDPBMC 6

Total CDGUT

CDGUT GFD

CDGUT active

study (Qiao et al.)11

study (Han et al.)7

study (Petersen et al.)15

repPC (Britanova et al.)14

Enriched Public clonotypes

CDPBMC

70

33

4

33

11

33

17

14

14

3

1

1

21

HCPBMC

95

95

5

51

26

36

37

26

24

0

0

0

47

CDGUT

60

30

0

15

8

13

30

15

30

0

1

0

15

Deriched public clonotypes

CDPBMC

75

38

3

38

38

16

18

10

17

0

0

0

22

HCPBMC

102

101

4

56

35

36

46

29

31

0

0

0

53

CDGUT

45

0

0

0

0

0

0

0

0

0

0

0

0

  1. +RankProduct(RP) results from approach two in the DA analysis.
  2. *Sequential forward feature (SFS) selection applied on the RP output resulting in differentially abundant (DA) clonotypes.