Figure 7
From: Urinary miR-21 as a potential biomarker of hypertensive kidney injury and fibrosis
Differential expression miR-21 in fibrotic and non-fibrotic tubules. The region of fibrotic and non-fibrotic tubules in the kidneys of mice treated with deoxycorticosterone acetate (DOCA)-salt for 8 days or the controls was collected using laser capture microdissection (LCM). (A) Representative images of kidney sections before and after LCM. (B) The levels of mRNA-21 expression in fibrotic and non-fibrotic tubules in the mice treated with DOCA-salt and tubules in the controls were measured, and 18 s rRNA is used as internal control. *P < 0.05 compared to the controls, n = 3, error bars represent mean ± SD.
