Figure 2 | Scientific Reports

Figure 2

From: Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy

Figure 2

PGE1 inhibited abnormal elevation of autophagy induced by PA. HK-2 cells were incubated with PA (0.5 mM) for 48 h, which was treated with PGE1 (0.1 ng/ml) for 24 hours. HK-2 cells in normal medium without PA were regarded as control group. Representative Western blot gel documents (a) and summarized data (b,c,d) showing the protein expression of LC3B, Beclin-1 and p62 in HK-2 cells. Typical fluorescent images (e) show the MDC staining HK-2 cells by confocal microscope and summarized data (f) showed the fluorescence intensity. *P < 0.05 vs. Ctrl; # P < 0.05 vs. PA treated group (n = 3).

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