Figure 4 | Scientific Reports

Figure 4

From: Human Placental-Derived Adherent Stromal Cells Co-Induced with TNF-α and IFN-γ Inhibit Triple-Negative Breast Cancer in Nude Mouse Xenograft Models

Figure 4

TNF-α/IFN-γ-Induced Human Placental-Derived ASCs Inhibit MDA-MB-231 Tumor Growth in Nude Mice. (a) Growth curves of tumor volume for MDA-MB-231 SubQ tumors in nude mice. Arrows mark days when TNF-α/IFN-γ-induced placental-derived ASCs were injected. (b) Growth curves of tumor volume for MDA-MB-231 mammary fat pad tumors in nude mice. The arrows mark days of the weekly IM injections of induced-ASCs. (c) Mean tumor volume at day 82 in the mammary fat pad model. (d) Percent change in mean tumor volume in the mammary fat pad model from the start of weekly IM injections of induced-ASCs. (e) Mean tumor mass at day 84 in the mammary fat pad model. n = 10 per group. Error bars are SEM. P-values are based on a one-tailed student’s t-test. Asterisks indicate p < 0.05.

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