Table 1 Demographic and clinical characteristics of subjects in the study groups.

From: Volatile molecules from bronchoalveolar lavage fluid can ‘rule-in’ Pseudomonas aeruginosa and ‘rule-out’ Staphylococcus aureus infections in cystic fibrosis patients

 

Study groups¥

p-value

Pa+

Sa+

NCM

Pa−

Sa−

P+ vs NCM

Sa+ vs NCM

Pa+/Sa+vs NCM

Pa+ vs Sa+

Pa+ vs Pa−

Sa+ vs Sa−

n

19

40

32

114

93

—

—

—

—

—

—

Age

17.6 (±8.6)

13.3 (±5.2)

9.8 (±6.9)

10.5 (±6.2)

11.4 (±7.5)

*0.03

0.74

0.25

0.12

**0.003

0.72

Gender (M/F)

9/10

25/15

15/17

55/59

39/54

1.00

0.74

0.51

0.66

1.00

0.19

Genotype (F508del/F508del / F508del/other)

6/7

15/14

13/7

66/41

53/34

0.64

0.82

0.51

1.00

0.60

0.72

BMI, kg/m2

20.0 (±2.8)

18.2 (±3.7)

17.6 (±2.7)

17.9 (±3.2)

18.2 (±2.9)

*0.03

0.82

0.25

0.12

**0.01

0.94

Comorbidities (Y/N)   Pancreatic insufficiency   CF-related diabetes

17/2

33/7

21/11

110/4

90/3

0.19

0.74

0.25

0.95

0.60

0.10

4/15

6/34

7/25

18/96

14/79

1.00

0.82

0.77

0.95

0.93

1.00

FVC % predicted Age ≥6 years

82.0 (±16.7) n = 18

94.6 (±15.6) n = 35

94.2 (±19.7) n = 22

91.5 (±18.8) n = 87

88.5 (±20.1) n = 69

0.07

0.82

0.51

0.12

0.08

0.72

FEV1% predicted Age ≥6 years

74.1 (±20.5) n = 18

87.1 (±17.9) n = 35

85.5 (±22.3) n = 22

83.4 (±20.7) n = 87

78.4 (±21.7) n = 69

0.19

0.82

0.50

0.13

0.16

0.22

  1. ¥Samples can belong to more than one study group.
  2. Data shown as mean (standard deviation) except where indicated.
  3. p-value <0.05*, 0.01** considered statistically significant after Benjamini-Hochberg correction.
  4. M, male; F, female, Y, yes; N, no; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s.
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