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Figure 1

From: Characterisation of the antibacterial properties of the recombinant phage endolysins AP50-31 and LysB4 as potent bactericidal agents against Bacillus anthracis

Figure 1

Results of survival rate and body temperature in in vivo study. A/J mice were infected intranasally with approximately 4 times the 50% lethal dose of spores of B. anthracis Sterne. At 6, 24, and 48 h post-infection, buffer (G1) or endolysin LysB4 (G2: 10 μg/head, G3: 100 μg/head) were administered intranasally (8 mice per group). Clinical signs of buffer- (A) or LysB4- (B) treated mice, survival rate (C), and body temperature (D) were observed. ***P < 0.001 compared to the G1 group.

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