Table 2 Structural effects in SLN prepared with different poloxamer 188 ratios, evaluated in terms of size (DLS) and concentration (NTA) of particles.

From: Use of nanoparticle concentration as a tool to understand the structural properties of colloids

Formulation

PL concentration (%)

Size (nm)

SLN concentration (particles/mL)

CP per SLN (molecules/particle)

SLN1

5

232.1 ± 2.7

61.3 ± 0.2 × 1012

2.0 × 106

SLN2

3

284.2 ± 9.9

33.6 ± 0.6 × 1012

3.7 × 106

SLN3

1

499.1 ± 0.4

27.2 ± 0.5 × 1012

4.6 × 106

SLN4

0.25

540.9 ± 20.5

23.3 ± 0.8 × 1012

5.4 × 106

SLN5

0.1

1644.3 ± 255.9

4.8 ± 0.1 × 1012

2.6 × 107

  1. The number of cetyl palmitate (CP) molecules per SLN was calculated from the number of nanoparticles and CP concentration in the formulation (mol/L).
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