Figure 8 | Scientific Reports

Figure 8

From: Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge

Figure 8

Reduced virulence of WU2ΔflaR Kan mutant. (a) Seven-week-old BALB/c mice were inoculated IP with 64 CFU of WU2 WT (n = 8) or 79 CFU of WU2ΔflaR Kan (n = 7) and survival was monitored daily (Log-rank (Mantel-Cox) test). (b) Seven-week-old CBA/Nxid mice were inoculated IP with 80 CFU of WU2 WT (n = 10) or WU2ΔflaR Kan (n = 8) and survival was monitored daily (Log-rank (Mantel-Cox) test *p = 0.0236).

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