Figure 5

Network configurations of ES and non-ES conditions. (a) A frequency configuration in the human brain network consisting of 82 brain regions. The asymmetric frequency distributions of the top 15 hub nodes are denoted with different colors. Each circle corresponds to a brain region, and the dark/gray lines are the connections among the regions. 82 regions are clustered into 10 larger brain regions, denoted in Supplementary Table S1. (b) The relationships between node degrees and frequencies for the ES and non-ES conditions. The ES condition has a V-shape relationship, in which the hub nodes have large and small frequencies suppressing synchronization until a critical point (the key mechanism of ES), whereas the non-ES condition has a random relationship. (c) The brain network model with ES conditions has positive degree-frequency correlation coefficient, larger frequency difference, and negative frequency assortativity compared to non-ES condition. Red solid lines throughout the panels are medians of 100 frequency configurations.